Acute Pain & Post-Operative

Post-operative pain remains a critical challenge in surgical recovery, impacting patient outcomes and satisfaction. Our Acute Pain research focuses on evaluating innovative therapies that improve pain control, reduce opioid reliance, and enhance recovery across diverse surgical populations.

Studies Conducted
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Active Centers
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Overview

Leading Acute Pain Clinical Research

Our acute pain clinical research combines scientific expertise with operational excellence to support post-operative studies from early-phase trials through late-stage development.

We specialize in designing trials that assess rapid-onset analgesics, non-opioid alternatives, and multimodal pain management strategies. Our teams ensure precise data collection, patient safety, and efficient execution across all study phases.

Our sites support a wide range of surgical models, enabling reliable evaluation of pain intensity, duration, and treatment response in real-world clinical settings.

Conditions Covered

Acute Pain Conditions We Research

Our acute pain research sites support a broad spectrum of post-operative and procedure-related pain conditions.

Post-Surgical Pain

Orthopedic Surgery Pain

Abdominal Surgery Pain

Dental Pain

Soft Tissue Injury Pain

Neuropathic Post-Surgical Pain

Acute Musculoskeletal Pain

Trauma-Related Pain

Burn Injury Pain

Post-Cesarean Pain

Our Approach

Why Sponsors Choose CenExel for Acute Pain

Our acute pain expertise goes beyond patient enrollment — we deliver scientific insight, rapid execution, and reliable outcomes.

01

Rapid Study Start-Up

Our experienced teams enable fast site activation and efficient study execution for time-sensitive acute pain trials.

02

Diverse Surgical Models

We support multiple surgical indications, providing flexibility and robust patient recruitment.

03

Opioid-Sparing Focus

Expertise in evaluating non-opioid and multimodal pain management strategies.

04

High Enrollment Performance

Consistent delivery of strong enrollment through targeted recruitment strategies.

Phase Coverage

Supported Trial Phases

We support acute pain clinical trials across all phases — from first-in-human studies to Phase IV post-marketing research, ensuring high-quality execution and reliable outcomes.

Active across all phases

Phase I

Phase II

Phase III

Phase IV

Our early phase capabilities include pharmacodynamic biomarker strategies, first-in-human studies, and proof-of-concept trial design — guided by Chief Scientific Officer Dr. Larry Ereshefsky, an internationally recognized KOL in CNS research with over 30 years of early phase expertise.

Let’s Advance Your Next Study

Looking for an experienced clinical research partner with the expertise, capabilities, and reach to move your study forward? Connect with CenExel to discuss your needs and explore how our network can support your clinical development goals.

Explore Our Network

Discover CenExel’s Centers of Excellence and find the locations, therapeutic expertise, and capabilities that align with your clinical development needs.