Acute Pain & Post-Operative
Post-operative pain remains a critical challenge in surgical recovery, impacting patient outcomes and satisfaction. Our Acute Pain research focuses on evaluating innovative therapies that improve pain control, reduce opioid reliance, and enhance recovery across diverse surgical populations.



Leading Acute Pain Clinical Research
Our acute pain clinical research combines scientific expertise with operational excellence to support post-operative studies from early-phase trials through late-stage development.
We specialize in designing trials that assess rapid-onset analgesics, non-opioid alternatives, and multimodal pain management strategies. Our teams ensure precise data collection, patient safety, and efficient execution across all study phases.
Our sites support a wide range of surgical models, enabling reliable evaluation of pain intensity, duration, and treatment response in real-world clinical settings.
Acute Pain Conditions We Research
Our acute pain research sites support a broad spectrum of post-operative and procedure-related pain conditions.
Post-Surgical Pain
Orthopedic Surgery Pain
Abdominal Surgery Pain
Dental Pain
Soft Tissue Injury Pain
Neuropathic Post-Surgical Pain
Acute Musculoskeletal Pain
Trauma-Related Pain
Burn Injury Pain
Post-Cesarean Pain
Why Sponsors Choose CenExel for Acute Pain
Our acute pain expertise goes beyond patient enrollment — we deliver scientific insight, rapid execution, and reliable outcomes.
01
Rapid Study Start-Up
Our experienced teams enable fast site activation and efficient study execution for time-sensitive acute pain trials.
02
Diverse Surgical Models
We support multiple surgical indications, providing flexibility and robust patient recruitment.
03
Opioid-Sparing Focus
Expertise in evaluating non-opioid and multimodal pain management strategies.
04
High Enrollment Performance
Consistent delivery of strong enrollment through targeted recruitment strategies.
Supported Trial Phases
We support acute pain clinical trials across all phases — from first-in-human studies to Phase IV post-marketing research, ensuring high-quality execution and reliable outcomes.
Active across all phases
Phase I
Phase II
Phase III
Phase IV
Our early phase capabilities include pharmacodynamic biomarker strategies, first-in-human studies, and proof-of-concept trial design — guided by Chief Scientific Officer Dr. Larry Ereshefsky, an internationally recognized KOL in CNS research with over 30 years of early phase expertise.
Let’s Advance Your Next Study
Looking for an experienced clinical research partner with the expertise, capabilities, and reach to move your study forward? Connect with CenExel to discuss your needs and explore how our network can support your clinical development goals.
Explore Our Network
Discover CenExel’s Centers of Excellence and find the locations, therapeutic expertise, and capabilities that align with your clinical development needs.
Therapeutic Area
Allergy & Immunology
Advancing clinical research for allergic, immunologic, and inflammatory conditions through experienced investigators,
Therapeutic Area
Cardiovascular Research
Cardiovascular diseases remain a leading cause of mortality worldwide, requiring innovative and precise clinical research.
Therapeutic Area
Chronic Pain
Chronic pain affects millions worldwide, significantly impacting quality of life and daily functioning.
